Publication '03 - '06

28. Tong, W. M., Lee, M. K., Galendo, D., Wang, Z. Q., & Sabapathy, K. (2006). Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice. International Journal of Cancer, 119(4), 745–749. https://doi.org/10.1002/ijc.21890

27. Siddique, M., & Sabapathy, K. (2006). Trp53-dependent DNA-repair is affected by the codon 72 polymorphism. Oncogene, 25(25),3489–500. https://doi.org/10.1038/sj.onc.1209405

26. Ihrlund, L. S., Hernlund, E., Viktorsson, K., Panaretakis, T., Barna, G., Sabapathy, K., Linder, S., & Shoshan, M. C. (2006). Two distinct steps of Bak regulation during apoptotic stress signaling: different roles of MEKK1 and JNK1. Experimental Cell Research, 312(9), 1581 1589. https://doi.org/10.1016/j.yexcr.2006.01.023

25. Siddique, M. M., Balram, C., Fiszer-Maliszewska, L., Aggarwal, A., Tan, A., Tan, P., Soo, K. C., & Sabapathy, K. (2005). Evidence for selective expression of the p53 codon 72 polymorphs: implications in cancer development. Cancer Epidemiology, Biomarkers & Prevention, 14(9), 2245 –2252. https://doi.org/10.1158/1055-9965.EPI-05-0153

24. Hu, Y., Wang, X., Zeng, L., Cai, D. Y., Sabapathy, K., Goff, S. P., Firpo, E. J., & Li, B. (2005). ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: implication of p27kip1 in cell response to oxidative stress. Molecular Biology of the Cell, 16(8), 3705–3718. https://doi.org/10.1091/mbc.e05-04-0301

23. Dulloo, I., & Sabapathy, K. (2005). Transactivation-dependent and independent regulation of p73 stability. The Journal of Biological Chemistry, 280(31), 28203–28214. https://doi.org/10.1074/jbc.M501702200

22. Vikhanskaya, F., Siddique, M. M., Kei Lee, M., Broggini, M., & Sabapathy, K. (2005). Evaluation of the combined effect of p53 codon 72 polymorphism and hotspot mutations in response to anticancer drugs. Clinical Cancer Research, 11(12), 4348–4356. https://doi.org/10.1158/1078-0432.CCR-04-1547

21. Chen, J. T., Lu, D. H., Chia, C. P., Ruan, D. Y., Sabapathy, K., & Xiao, Z. C. (2005). Impaired long-term potentiation in c-Jun N-terminal kinase 2-deficient mice. Journal of Neurochemistry, 93(2), 463–473. https://doi.org/10.1111/j.1471-4159.2005.03037.x

20. Toh, W. H., Kyo, S., & Sabapathy, K. (2005). Relief of p53-mediated telomerase suppression by p73. The Journal of Biological Chemistry, 280(17), 17329–17338. https://doi.org/10.1074/jbc.M500044200

19. Lee, M. K., Hande, M. P., & Sabapathy, K. (2005). Ectopic mTERT expression in mouse embryonic stem cells does not affect differentiation but confers resistance to differentiation- and stress-induced p53-dependent apoptosis. Journal of Cell Science, 118(Pt 4), 819–829.https://doi.org/10.1242/jcs.01673

18. Sabapathy, K., & Wagner, E. F. (2004). JNK2: a negative regulator of cellular proliferation. Cell Cycle, 3(12), 1520–1523. https://doi.org/10.4161/cc.3.12.1315

17. Toh, W. H., Siddique, M. M., Boominathan, L., Lin, K. W., & Sabapathy, K. (2004). c-Jun regulates the stability and activity of the p53 homologue, p73. The Journal of Biological Chemistry, 279(43), 44713–44722. https://doi.org/10.1074/jbc.M407672200

16. Lin, K. W., Nam, S. Y., Toh, W. H., Dulloo, I., & Sabapathy, K. (2004). Multiple stress signals induce p73beta accumulation. Neoplasia, 6(5), 546–557. https://doi.org/10.1593/neo.04205

15. Sabapathy, K., Hochedlinger, K., Nam, S. Y., Bauer, A., Karin, M., & Wagner, E. F. (2004). Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun- dependent cell proliferation. Molecular Cell, 15(5), 713–725. https://doi.org/10.1016/j.molcel.2004.08.028

14. Li, G., Xiang, Y., Sabapathy, K., & Silverman, R. H. (2004). An apoptotic signaling pathway in the interferon antiviral response mediated by RNase L and c-Jun NH2-terminal kinase. The Journal of Biological Chemistry, 279(2), 1123–1131. https://doi.org/10.1074/jbc.M305893200